Promethazine hydrochloride and codeine phosphate syrup is indicated with the temporary reduction of coughs and upper respiratory indications affiliated with allergy or maybe the popular cold.
Promethazine with Codeine Oral Answer has promethazine, a phenothiazine. Phenothiazines are involved with dystonic reactions, significantly in pediatric people which have an acute health issues affiliated with dehydration.
Codeine and its salts are well absorbed following each oral and parenteral administration. Codeine is about 2/three as effective orally as parenterally. Codeine is metabolized primarily within the liver by enzymes from the endoplasmic reticulum, exactly where it undergoes O-demethylation, N-demethylation, and partial conjugation with glucuronic acid.
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Promethazine with Codeine Oral Remedy has codeine, a Routine V managed material. As an opioid, Promethazine with Codeine Oral Remedy exposes consumers to your challenges of habit, abuse, and misuse [see DRUG ABUSE AND DEPENDENCE (9)], which can lead to overdose and death [seeOVERDOSAGE (10)]. Reserve Promethazine with Codeine Oral Remedy for use in adult people for whom the key benefits of cough suppression are envisioned to outweigh the hazards, and in whom an ample evaluation of your etiology of the cough has become designed. Evaluate Every patient's threat just before prescribing Promethazine with Codeine Oral Solution, prescribe Promethazine with Codeine Oral Option for the shortest period that is certainly regular with personal individual procedure ambitions, check all clients frequently for the development of habit or abuse, and refill only after reevaluation of the need for continued procedure.
Codeine may well increase the neuromuscular blocking motion of skeletal muscle mass relaxants and make an elevated diploma of respiratory depression.
Uncontrolled spasms within your face and neck muscles, or muscles of Your whole body, arms, and legs (dystonia). These muscle mass spasms can result in irregular movements and human body positions, and speech troubles. These spasms may materialize soon after a single dose of click here PROMETHAZINE WITH CODEINE ORAL Alternative. Tell your healthcare supplier When you have any of such symptoms. Amplified possibility of seizures in people with seizure Issues. Should you have a seizure condition, PROMETHAZINE WITH CODEINE ORAL Resolution may well raise how frequently you may have seizures. Low blood pressure. A unexpected fall in hypertension can occur in many people through remedy with PROMETHAZINE WITH CODEINE ORAL Answer and this might result in you to sense dizzy, faint, lightheaded, or weak, especially when you stand up (orthostatic hypotension).
Tend not to flush down a rest room or pour down a drain Except if you're advised to do so. Look at with your pharmacist Should you have questions on The obvious way to toss out medication. There may be drug acquire-again applications in your area. Buyer Information and facts Use and Disclaimer
Be certain you know how to choose this products and what other medicines you should steer clear of getting with it. See also Drug Interactions portion. Get professional medical enable without delay if any of these really severe Uncomfortable side effects occur: slow/shallow breathing, abnormal lightheadedness, critical drowsiness/dizziness, issue waking up.
Tend not to increase your dose or use this product or service much more frequently or for extended than prescribed. Your problem will not improve any speedier, as well as your chance of Unwanted side effects will maximize.
Drug interactions may possibly change how your remedies operate or increase your chance for really serious Unwanted effects. This doc will not consist of all feasible drug interactions.
There isn't a normal agreement about distinct pharmacological procedure regimens for uncomplicated NMS.
The Promethazine VC with Codeine brand name title has been discontinued within the U.S. If generic variations of this solution have been accepted via the FDA, there might be generic equivalents available.
Explain to your medical professional When your cough isn't going to recover in 5 times. Also, convey to your health practitioner If the issue gets even worse, or When you've got a headache that does not go away, fever, or rash. These could possibly be signs or symptoms of a serious healthcare problem and may be checked by a doctor.